Functional MRI today.

A Brief Introduction to Functional MRI History and Today ’ s Developments

MRI catheterization in cardiopulmonary disease.

Diagnosis and prognostication in patients with complex cardiopulmonary disease can be a clinical challenge. A new procedure, MRI catheterization, involves invasive right-sided heart catheterization performed inside the MRI scanner using MRI instead of traditional radiographic fluoroscopic guidance. MRI catheterization combines simultaneous invasive hemodynamic and MRI functional assessment in a...

Brain Single Photon Emission Computed Tomography Scan (SPECT) and Functional MRI in Systemic Lupus Erythematosus Patients with Cognitive Dysfunction: A Systematic Review

Objective(s): Systemic lupus erythematosus (SLE) is an autoimmune disease with a wide range of clinical manifestations. Cognitive dysfunction is one of the manifestations that could present prior to the emergence of any other neuropsychiatric involvements in SLE. Cognitive dysfunction is a subtle condition occurring with ahigh frequency. However, there is no data on the correlation of cognitive...

Magnetic resonance imaging in drug discovery: lessons from disease areas.

Imaging technologies are presently receiving considerable attention in the pharmaceutical area owing to their potential to accelerate the drug discovery and development process. One of the principal imaging modalities is magnetic resonance imaging (MRI). The multiparametric nature of MRI enables anatomical, functional and even molecular information to be obtained non-invasively from intact orga...

PET/MRI: the blended-modality choice of the future?

This article addresses the emerging technology of PET coupled with MRI, or PET/MRI, which could become the technology of choice in the future for many reasons. Some of these reasons will be discussed, along with a historical account of the field of MRI and how this modality has evolved to include many aspects of molecular and functional imaging. After reading this article, nuclear medicine tech...

High field MRI in clinical practice.

Magnetic resonance imaging and spectroscopy can provide detailed morphologic, functional and metabolic information that may provide unique biomarkers to assist drug discovery and development. To overcome the inherent low signal to noise of in vivo magnetic resonance applications, stronger magnetic field strengths can be applied that not only boost signal strengths, but can also be used to impro...